Getting Started: A Quick Guide set up Microsoft Defender

Here’s a quick guide to help you set up Microsoft Defender and configure Exchange policies to secure your organization’s email and data:


1. Set Up Microsoft Defender for Office 365

Step 1: Assign Licenses

  • Ensure your organization has the necessary licenses for Microsoft Defender for Office 365.
  • Assign licenses to the required users through the Microsoft 365 admin center.

Step 2: Configure Microsoft Defender

  1. Access Security & Compliance Center:
  2. Set Up Threat Policies:
    • Go to Policies & Rules > Threat Policies.
    • Configure the following:
      • Anti-Phishing Policy: Protect users from phishing attacks.
      • Anti-Spam Policy: Block spam and unwanted email.
      • Anti-Malware Policy: Ensure emails and files are scanned for malware.

Step 3: Configure Safe Links and Safe Attachments

  • Safe Links: Protect users from malicious URLs in emails.
    • Navigate to Safe Links, and define which links should be scanned or blocked.
  • Safe Attachments: Scan email attachments for threats.
    • Turn on and enforce the Safe Attachments policy.

Step 4: Enable Real-Time Reporting

  • Monitor threats using the Threat Explorer and Real-Time Reports for a comprehensive overview of email activity.

2. Configure Exchange Online Policies

Step 1: Access Exchange Admin Center

Step 2: Set Up Mail Flow Rules (Transport Rules)

  1. Navigate to Mail Flow > Rules.
  2. Add rules to control and secure email flow:
    • Block specific file types or extensions (e.g., .exe, .bat).
    • Redirect suspicious emails for admin review.
    • Encrypt sensitive emails automatically.

Step 3: Enable Data Loss Prevention (DLP)

  • Use DLP policies to protect sensitive information like credit card numbers or personal identification data.
    1. Go to Compliance Center > Data Loss Prevention.
    2. Create a policy to monitor, alert, or block the sharing of sensitive information.

Step 4: Configure Outbound Spam Protection

  • Prevent compromised accounts from sending spam:
    • Navigate to Protection > Outbound Spam.
    • Set thresholds for outbound email limits and enable alerts for suspicious activity.

3. Additional Security Recommendations

  • Multi-Factor Authentication (MFA):
    • Enforce MFA for all users to reduce the risk of unauthorized access.
    • Set up MFA through Azure Active Directory in the Microsoft 365 admin center.
  • Quarantine Notifications:
    • Configure quarantine notifications to inform users of emails blocked by policies.
  • Audit Logs:
    • Enable and review audit logs to monitor changes and access to sensitive data.

By following these steps, you’ll establish a secure environment for your organization, safeguarding emails and sensitive data against common threats. If you’d like a detailed policy checklist or further customization, let me know!

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